https://www.selleckchem.com/pr....oducts/k-ras-g12c-in
Molecular characterization in pediatric papillary thyroid cancer (PTC), distinct from adult PTC, is important for developing molecular targeted therapies for progressive 131I-refractory PTC. PTC samples from 106 pediatric patients (age 4.3-19.8 years; 21 boys) who attended Seoul National University Hospital (January 1983-March 202 were available for genomic profiling. Previous transcriptome data from 125 adult PTCs were used for comparison. Genetic drivers were found in 80 tumors; 31 with fusion oncogenes (RET in 21, ALK
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