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Rates of patient portal messaging did not differ between English-speaking and LEP groups on multivariable analysis; however, patients with LEP were less likely to have a portal account (adjusted OR, 0.89; 95% CI, 0.83 to 0.96). Among LEP subgroups, Spanish speakers were significantly less likely to engage with the patient portal compared with English speakers (estimated difference in monthly rate OR, 0.43; 95% CI, 0.24 to 0.77). We found that patients with LEP had lower rates of clinical trial engagement and odds of electronic patient port
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