https://www.selleckchem.com/products/bi-4020.html
The content of miR-494 in peripheral blood decreased. The insulin concentration in the supernatant of INS-1 cells overexpressing miR-494 increased. When high glucose was given, the overexpression of miR-494 further promoted insulin secretion. Overexpression of miR-494 significantly promoted INS-1 cell activity and inhibited INS-1 cell apoptosis. miR-494 significantly promoted the protein expression of Wnt3a, β-catenin, cyclin D1 and c-Myc. miR-494 inhibitor treatment showed the opposite results. Conclusion miR-494 promotes islet β cell
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