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ROC curve analyses indicated 3.5-6.5 as the optimal range of PRBQ cutoff scores. Thus, the PRBQ has good ability to discriminate participants endorsing (vs. not) clinical levels of alcohol/drug misuse, disordered eating, problematic gambling, and compulsive buying (lowest accuracy in identifying participants with clinical levels of alcohol misuse), and a minimum cutoff score between 3.5 and 6.5 may suggest using additional diagnostic assessments and clinical interventions.We evaluated the clinical validity of a combinatorial pharmacoge
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