https://www.selleckchem.com/pr....oducts/gsk269962.htm
Sanger sequencing confirmed the stallion was heterozygous for the MITF deletion. No SNPs or structural variants were identified in PAX3 or any of the other candidate genes that were unique to the stallion or predicted to affect protein function. Genotyping five of the stallion's splashed white offspring, including one all white foal, found that they were also heterozygous for the deletion. Given the role of MITF in producing white pattern phenotypes, and the predicted deleterious effect of this mutation, this 8.7 kb deletion is the li
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