https://garciniacambogiachemic....al.com/examination-o
CD27 signaling was particularly very important to the thymic development and peripheral homeostasis of Foxp3+Helios+ regulatory T cells, which likely accounts for our finding that CD70-deficient NOD mice develop more-aggressive T1D onset. Interestingly, we found that CD27 signaling suppresses the thymic development and effector features of T1D-protective invariant NKT cells. Hence, as opposed to providing costimulatory signals, the CD27-CD70 axis may portray a coinhibitory path for this immun
Respect!
Kommentar
Delen
