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We review the fungal and metazoan unconventional secretory pathways and their regulation, and propose experimental criteria to identify their mode of secretion.In this study, predictive models are proposed to accurately estimate the confirmed cases and deaths due to of Corona virus 2019 (COVID-19) in Africa. The study proposed the predictive models to determine the spatial and temporal pattern of COVID 19 in Africa. The result of the study has shown that the spatial and temporal pattern of the pandemic is varying across in the study are
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