https://www.selleckchem.com/pr....oducts/Staurosporine
Discriminatory drug delivery into target cells is essential to effectively elicit the drug activity and to avoid off-target side effects; however, transporting drugs across the cell membrane is difficult due to factors such as molecular size, hydrophilicity, intercellular adhesiveness, and efflux transporters, particularly, in the brain capillary endothelial cells. Drug delivery into the brain is blocked by the blood-brain barrier (BB. Thus, developing drugs for the central nervous system (CNS) diseases remains a challenge. The
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