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4 and 27.0 years (pooled median 19.0 years, 95% CI 18.0-20.9; weighted pooled median 19.4 years, 18.2-20.1). Median life expectancy with ventilatory support, introduced in most settings in the 1990s, ranged between 21.0 and 39.6 years (pooled median 29.9 years, 26.5-30.8; weighted pooled median 31.8 years, 29.3-36.2). Risk of bias had little impact on pooled results. In conclusion, median life expectancy at birth in DMD seems to have improved considerably during the last decades. With current standards of care, many patients with DMD ca
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