https://www.selleckchem.com/pr....oducts/bgj398-nvp-bg
Our results are focused on a detailed description of the pore formation by Pin2 in POPC and POPEPOPG membranes., which strongly suggest that Pin2 forms a toroidal pore and not a barrel-shaped pore; this type of pore also affects the membrane properties. In the process, a phospholipid remodeling in the POPEPOPG membrane takes place. Moreover, the pores formed by Pin2 indicate that they are selective for the chlorine ion. There are no previous ion selectivity reports for other AMPs with similar physicochemical properties, such a
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