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In the case of failed MSIs, the levels of TGF-β1 at various time periods were approximately constant and of much lower value than corresponding time periods of successful MSIs. This study highlights the role of TGF- β1 in bone metabolism around miniscrew reflecting the state of inflammation from 1 h post-implantation. © 2020 Craniofacial Research Foundation. Published by Elsevier B.V. All rights reserved.Objectives Chondrosarcomas are malignant bone tumors considered as resistant to radiotherapy. To unravel mechanisms of resistance, we
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