https://www.selleckchem.com/pr....oducts/tuvusertib.ht
Then, the fibroblasts were treated with the Pan-Akt inhibitor (GDC-0068), and we surprisingly found that GDC-0068 abrogated the inhibiting effects of Fasudil on cell autophagy and proliferation in the PUFs treated with TGF-β. Fasudil regulated Akt/mTOR pathway mediated autophagy to hamper TGF-β-mediated super-activation in PUFs, which supported that Fasudil might be an ideal candidate therapeutic agent for TUS treatment for clinical utilization. Fasudil regulated Akt/mTOR pathway mediated autophagy to hamper TGF-β-mediated super-acti
Beğen
Yorum Yap
Paylaş
