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However, both the MAMs dysfunction and the IP3 signaling dysregulation combined can lead to a robust Ca2+ signal and improper glucose release. In addition, our model results suggest a strong dependence of Ca2+ oscillations pattern on morphological characteristics of the ER and the mitochondria.A non-smooth SIR Filippov system is proposed to investigate the impacts of three control strategies (media coverage, vaccination and treatment) on the spread of an infectious disease. We synthetically consider both the number of infected population and its changing ra
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