https://www.selleckchem.com/products/AZD6244.html
Computational modeling suggests that C-10 binds to unique sites in α-synuclein which may interfere in its aggregation amplification. These findings open an avenue for comprehensive SAR development for flavonoid glycosides as pharmacological chaperones for metastable and aggregation-prone proteins implicated in protein conformational diseases. Congenital bronchial atresia (CBA) is a rare airway malformation. No management guidelines exist because of limited evidence treatment, surgical or conservative, is based on consensus and opinion.
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