https://www.selleckchem.com/
The regulation of sarcomere assembly by integration of incoming signaling pathways causing the same PTMs or ligand binding are discussed in response to mechanical loading and unloading by the Z-disc proteins CapZ, α-actinin, telethonin, titin N-termini, and others. Many human mutations that lead to cardiomyopathy and heart disease occur in the proteins discussed above, which often occur at their PTM or ligand binding sites. The role of angiotensin receptor blockers (AR, angiotensin-converting enzyme inhibitors (ACEi), or other antihypertensive agents in t
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