https://www.selleckchem.com/pr....oducts/1-methylnicot
on-replicative adenovirus encoding mTNFα and mIL-2 potentiates ICI therapy, demonstrated by improved tumor growth control and survival in head and neck tumor-bearing mice. Moreover, the data reveals a potential approach for inducing tertiary lymphoid structure formation. Altogether our results support the clinical potential of combining this adenovirotherapy with anti-PD-1 or anti-PD-L1.The NF-κB transcription factor family controls the transcription of many genes and regulates a number of pivotal biological proces
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