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Despite the small differences in single genes' expression, gene set enrichment analysis showed coordinated gene expression differences associated with several pathways differentially regulated in the two selection lines. High sperm production males showed an upregulation of pathways related to immunosuppression and development of spermatozoa indicating a possible immunological cost of sperm production. © 2020 Wiley Periodicals, Inc.AIM Patients with primary Sjögren's syndrome (pSS) have an increased risk of developing diffuse large B-ce
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