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21 (P.001), 0.16 (P .001), and 0.25 (P=.001), respectively. Of patients who develop subsequent cSCC, 18.06% do so within 6months, and 31.77% do so within 1year of initial cSCC diagnosis. Patients with advanced age, poor histologic differentiation, and American Joint Committee on Cancer T2 stage are at highest risk. Close clinical follow-up after the initial diagnosis is recommended. Of patients who develop subsequent cSCC, 18.06% do so within 6 months, and 31.77% do so within 1 year of initial cSCC diagnosis. Patients with advanced a
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