https://www.selleckchem.com/pr....oducts/cirtuvivint.h
sis by pre-treatment with the ER-stress inducer tunicamycin and LPS. mice treated with CCl + LPS were significantly protected from multi-organ injury compared to wild-type CCl + LPS. These data demonstrate for the first time a causal relationship between LPS-mediated activation of caspase(s)-4/11 and development of hepatic and extra-hepatic injury in cirrhosis. These data demonstrate for the first time a causal relationship between LPS-mediated activation of caspase(s)-4/11 and development of hepatic and extra-hepatic injury in cirr
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