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OBJECTIVE To consider the acceptability and content validity of patient-reported outcome measures (PROMs) commonly used in rheumatoid arthritis (RA) by describing patients' perceptions of PROMs, and comparing patients' PROM responses with their verbal accounts of disease impacts. METHODS We used a sequential mixed methods approach, combining analysis of interviews and PROM data (HAQ, FACIT-F, EQ-5D, SF36, and VAS for pain, fatigue, sleep, and patient global). Qualitative analysis of patients' perceptions of PROMs informed a subsequent
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