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Wild-type canine distemper virus (CDV) is an important pathogen of dogs in addition to wildlife that may infect resistant and epithelial cells through two understood receptors the signaling lymphocytic activation molecule (SLAM) and nectin-4, respectively. Conversely, the ferret and egg-adapted CDV-Onderstepoort strain (CDV-OP) is required as a highly effective vaccine for dogs. CDV-OP also shows promising oncolytic properties, such its abilities to infect and eliminate several cancer tumors cel
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