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Structural models of mental illness delineate the major phenotypic dimensions of psychopathology. These evidence-based models, such as the Hierarchical Taxonomy of Psychopathology, are poised to supplement-and even supplant-categorical diagnostic systems in research, assessment and treatment arenas. This special issue of Personality and Mental Health explores a new wave of research into structural models' utility for theory testing and clinical practice. Can structural approaches advance etiological research by clarifying
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