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8% v 0.8%, p = 0.016, and 7.2% v 0.8%, p = 0.022, respectively). FC management-related thromboembolic events were not registered. The FC strategy was associated with a 2.19-fold decrease in the odds of massive postoperative bleeding (p 0.0001), a 2.56-fold decrease in the odds of polytransfusion (p 0.0001), and a 13.16-fold decrease in the odds of early postoperative death (p = 0.003). FC-based versus blood product-based management is associated with reduced blood product needs and fewer complications, and was not linked to a h
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