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They also argue against disengagement of the N-domain out of the channel as a rigid body, and suggest instead that it remains within the transmembrane pore as FeEnt enters the periplasm. Published under license by The American Society for Biochemistry and Molecular Biology, Inc.Exogenous and endogenous chemicals can react with DNA to produce DNA lesions that may block DNA replication. Not much is known about the roles of polymerase (Pol) ν and Pol θ in translesion synthesis (TLS) in cells. Here, we examined the functions of both polymer
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