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vival. Of interest, spindle cell type and TILs 30% are revealed as independent negative prognostic factors, and further molecular mechanisms need to be explored.Pancreatic ductal adenocarcinoma (PDAC) is aggressive, with an overall five-year survival rate of 9%, and few patients are candidates for pancreatectomy at presentation. The role of neoadjuvant therapy (NAT) is evolving, especially for high-risk potentially resectable tumors. Owing to the increasing number of NAT resection specimens, we aim to characterize the histologic cha
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