https://www.selleckchem.com/products/t-5224.html
Coronary artery disease (CAD) is a complex disease with a strong genetic basis. While previous studies have combined common single-nucleotide polymorphisms (SNPs) into a polygenic risk score (PRS) to predict CAD risk, this association is poorly characterised. We performed a meta-analysis to estimate the effect of PRS on the risk of CAD. Online databases were searched for studies reporting PRS and CAD. PRS computation was based on log-odds (PRS ), pruning or clumping and thresholding (PRS ), Lassosum regression (PRS ), LDpred (PRS ), or m
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