https://www.selleckchem.com/pr....oducts/ly2157299.htm
This study chronologically evaluated the expression of the intensity and distribution of the sigma-1 receptor (σ1R) demonstrated by radiolabeled 2-[4-(2-iodophenyl)piperidino]cyclopentanol (OI5V) in a rat model of myocardial ischemia and reperfusion.Methods and ResultsThe left coronary artery was occluded for 30 min, followed by reperfusion. Dual-tracer autoradiography with I-OI5V and Tc-MIBI was performed to assess the spatiotemporal changes in I-OI5V uptake (n=5-6). Significant and peaked I-OI5V uptake in the ischemic area was obser
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