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3 ± 14.5years) were included; five had rectal and four had tumors in the sigmoid colon. The median SMSA score was 14 (SMSA Level IV-complex polyp), while three patients were pre-treated with EMR. DEA-ESD was technically feasible in all cases. En bloc resection and R0 resection rates were 100%, respectively, with a mean procedure time of 128.4 ± 54.1 min. No immediate or delayed complications occurred. DEA-ESD is a feasible and safe method for treating complex or recurrent tumors in the rectum and distal colon. DEA-ESD is a feasible and s
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