https://www.selleckchem.com/pr....oducts/n-ethylmaleim
In the huBM ex vivo culture, addition of IL-6 and IL-15 to CP inhibited the proliferation stages of erythropoiesis, whereas TNFα supplementation caused maximum diminution at erythroblast enucleation stage. Supplementation with anti-TNFα in the BP showed significant but partial restoration in the enucleation process, revealing the possibility of other crucial microenvironmental factors that could impact RBC production in burn patients. Exogenous TNFα impairs late-stage erythropoiesis by blocking enucleation, but neutralizati
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