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3% versus 30.4% and 10.5% versus 25.0%, respectively (p 0.001). The rates of ≥ grade 3 leukopenia and radiation esophagitis in the CCRT group were higher than that of RT alone group (p 0.05). There was no significant difference in the probability of radiation pneumonitis between the two groups (p=0.167). Multivariate Cox analysis indicated that female, EQD2 ≥60 Gy and concurrent chemotherapy were favorable prognostic factors for both OS and PFS. Concurrent chemotherapy can bring survival benefits to patients with locally advance
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