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Furthermore, a significantly increased distribution of A/A (rs4693608) had been noticed in patients with grade≥2 (p=.03) and in customers with positive cervical intrusion (p=.042) while customers with T/C (rs4364254) had lower tumor level. Our study suggested that HPSE SNP of rs4693608 correlated highly with susceptibility to EC, and HPSE SNPs might be a potential biomarker for prognosis of endometrial disease.Our research advised that HPSE SNP of rs
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