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To study the medial rectus (MR) muscle of zebrafish ( ) with respect to the pattern of distribution of desmin and its correlation to distinct types of myofibers and motor endplates. The MRs of zebrafish were examined using confocal microscopy in whole-mount longitudinal specimens and in cross sections processed for immunohistochemistry with antibodies against desmin, myosin heavy chain isoforms, and innervation markers. Desmin patterns were correlated to major myofiber type and type of innervation. A total of 1382 myofibers in nine MR mu
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