https://faah-signal.com/checki....ng-out-the-partnersh
We hypothesized that supraphysiological degrees of testosterone, via generation of mitochondrial reactive oxygen types (mROS), triggers the NLRP3 inflammasome and promotes vascular disorder. Practices Male, 12 week-old C57Bl/6J (WT) and NLRP3 knockout (NLRP3-/-) mice were used. Mice were treated with testosterone propionate [TP (10 mg/kg) in vivo] or vehicle for 1 month. In addition, vessels had been incubated with testosterone [Testo (10-6 M, 2 h) in vitro]. Testosterone levels, blood circulation pre
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