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Stroma PD-L1 (P = 0.03, vimentin (P = 0.026) expression, and CD8+ T cell infiltration (P less then 0.001) were independent prognostic factors in mRCC. High vimentin expression was accompanied by high PD-1, PD-L1 expression, and increased regulatory T cell infiltration (all P less then 0.001), indicating immunosuppression in the tumor microenvironment. Conclusions We revealed that vimentin expression was associated with immunosuppression in mRCC, and the immune-suppressive status might be possibly posed by PD-1/PD-L1. Patients with hig
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