https://www.selleckchem.com/pr....oducts/resatorvid.ht
The volume fraction of the extracellular matrix (ECM) within the layer of airway smooth muscle (ASM) is increased in subjects with fixed airflow obstruction. We postulated that changes in ECM within the ASM layer will impact force transmission during induced contraction and / or in response to externally applied stresses like a deep inspiration (DI). Subjects were patients undergoing lung resection surgery who were categorized as unobstructed (n=12) or obstructed 'fixed' (n=6), based on pre-operative spirometry. The response to a DI,
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