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Such structures are created by G-rich DNA sequences typified by telomeric DNA repeats. Whilst there is certainly research for proteins that bind and control G-quadruplex formation, the molecular basis with this stays badly understood. The budding fungus telomeric necessary protein Rap1, initially defined as a transcriptional regulator operating by recognizing double-stranded DNA binding websites, had been one of the first proteins to be found to also bind and advertise G-q
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