https://www.selleckchem.com/pr....oducts/Obatoclax-Mes
CH⋯O hydrogen bonds constitute a unique class of cohesive interactions. Their properties are similar to those of canonical H-bonds, although their energy is significantly lower, typically in the 0.5-2.5 kcal/mol range. Polarised CH groups, such as those adjacent to electronegative groups, or within aromatic moieties, are particularly strong donors. CH⋯O bonds are ubiquitous in nucleic acids and in proteins, notably stabilizing the β-sheet secondary structure. They have also been observed in numerous protein-ligand interact
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