https://www.selleckchem.com/products/OSI-906.html
Despite advances in cancer diagnosis and therapeutics, the overall 5-year survival rate of oral squamous cell carcinoma (OSCC) remains low. Tumor formation, progression, recurrence, and chemo-resistance are associated with the presence of cancer stem cells (CSC) that show phenotypic heterogeneity, but how they influence tumor behavior remains poorly understood. We aimed to describe how two CSC phenotypes from an OSCC cell line, CD44 ESA (Epi-CSC) and CD44 ESA (EMT-CSC), behave in vitro and in vivo. In vitro behavior of FACS-sorted Epi-C
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