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the moderate group (p less then 0.05) and the normal vs. the severe group (p less then 0.01). There was a significant inverse correlation between the CMAP-12 amplitude and overall survival. Compared to that in the normal group, survival in the moderately and severely decreased groups was significantly shorter (HR 3.394, 95% CI 1.292-8.917, p = 0.013; and HR 4.732, 95% CI 2.032-11.017; p = 0.000, respectively). Conclusions Our results suggest that CMAP-12 amplitude could be a prognostic indicator of disease progression in ALS. More importantly, our findings
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