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Outdoor air pollution contributes to asthma development and exacerbations; yet, its effects on airway pathology have not been defined in children. To explore the possible link between air pollution and airway pathology, we examined retrospectively the relation between environmental pollutants and pathological changes in bronchial biopsies of children undergoing a clinically indicated bronchoscopy. Structural and inflammatory changes (Basement Membrane-BM thickness, epithelial loss, eosinophils, neutrophils, macrophages, mast-cells, lymph
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