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Multivariate analysis revealed that age, radiological response, and LIP-SVM were independent factors for MPR in the two sets (each P less then 0.05). The integration of LIP-SVM, clinical factors, and radiological response showed significantly high accuracies for predicting MPR in discovery and validation sets (AUC = 0.951, 95% CI 0.916-0.986, P less then 0.001; AUC = 0.943, 95% CI 0.912-0.993, P less then 0.001, respectively). Based on immune cell profiling of peripheral blood, our study developed a predictive model for the MPR of patie
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