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Conclusions Higher serum DHEAS concentrations already at age 1 year are associated with those at age 6 years. Also, shorter birth length and rapid catch-up growth in length by age 1 year are associated with higher DHEAS concentrations at age 6 years. These results corroborate the early origin of adrenarche and strongly suggest that part of adrenarchal programming already takes place by the end of infancy. © Endocrine Society 2020.Because of its rarity, our understanding of steroidogenesis in estrogen-producing adrenocortical adenoma, in
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