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To investigate the effect of local treatment strategy on survival outcome in stage IV breast cancer patients who received chemotherapy. We identified stage IV breast cancers that presented with synchronous metastasis from the Surveillance, Epidemiology, and End Results database. Binomial logistic regression, Kaplan-Meier survival curves, propensity score matching (PSM), and multivariate Cox regression model were used for statistical analyses. We identified 5,374 patients in total, including 2,319 (43.2%), 2,137 (39.8%), and 918 (17.1%)
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