https://www.selleckchem.com/pr....oducts/smoothened-ag
Quantitative μCT showed similar bone volume (median 8.0 mm , interquartile range 7.0-10.0 vs. 6.2 mm , 4.3-9.4, p = 0.06) and trabecular thickness (0.21 mm, 0.19-0.23 vs. 0.18 mm, 0.17-0.20, p = 0.03) between upside-down and regular placement, both leading to an almost complete bony coverage. Histomorphometry showed comparable new bone areas between the upside-down and regularly placed membranes, 3.9 mm (2.7-5.4) vs. 3.8 mm (2.2-4.0, p = 0.31), respectively. Both treatment groups revealed the same regeneration pattern
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