https://www.selleckchem.com/pr....oducts/LY315920(Vare
Asymmetric reductive amination is one of the most important reactions in the preparation of chiral amine pharmaceutical intermediates. #link# Different kinds of enzymes have been applied to the synthesis of chiral amines Among them, the development of reductive amination reactions catalyzed by NAD(P)H-dependent oxidoreductases is attractive, as it would permit a one-step transformation of prochiral ketones into chiral amines with high optical purity. In this review, the recent advances in enzyme structure, catalytic mechan
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