https://www.selleckchem.com/pr....oducts/sch772984.htm
55 ± 0.06 (plaque), of 8 0.28 ± 0.06 µM and 0.42 ± 0.07, and of 9 0.30 ± 0.05 µM (luciferase) and 0.35 ± 0.07 (plaque). The CC50 for 7, 8, and 9 in non-infected human foreskin fibroblasts was 500µM, yielding a selectivity index of 1500. Compounds 1, 7, and 8 were also tested in CMV-infected primary human hepatocytes and showed a dose-response against CMV by luciferase activity and viral protein expression. None of the active compounds inhibited herpes simplex virus 1 or 2. Compounds 7 and 8 inhibited mouse CMV replication in
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