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To review the association between US e-cigarette regulations and the number of reported nicotine exposures, and identify higher-risk products DESIGN Retrospective review of de-identified medical records. California PARTICIPANTS Cases reported to California Poison Control System in 2012-2018. Suspected nicotine toxicity; route of exposure and product characteristics. We examined 5277 exposures, of which 3033 involved combustible cigarettes, 1489 involved e-cigarettes and 818 involved other substances (ie, chewing tobacco, nicotine patche
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