https://www.selleckchem.com/pr....oducts/Docetaxel(Tax
AIM Hypoxia-inducible factor (HIF)1α is induced by endothelial cells under hypoxic conditions, suggesting that HIF1α may be involved in vascular impairment in patients with systemic sclerosis (SSc). The purpose of this study was to evaluate whether single nucleotide polymorphisms (SNPs) of the HIF1A gene are associated with susceptibility to SSc and its complications, including pulmonary arterial hypertension (PAH). METHOD This study involved 182 Japanese SSc patients (discovery cohort) and 178 healthy controls. Four SNPs (r
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