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32, 95%CI -0.49, -0.14, I2=58%, p less then 0.001) compared to minimal care for people with OA. For knee OA there was low to moderate credibility evidence that weight loss interventions were not more effective than exercise only for pain intensity or disability (4 trials n=673, SMD -0.13, 95%CI -0.40, 0.14, I2= 55%; 5 trials, n=737, SMD -0.20 95%CI -0.41, 0.00, I2= 32%). CONCLUSIONS Weight loss interventions may have small to moderate improvements on pain and disability for OA compared to minimal care. There was limited and inconclusiv
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