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ppearance to the alveolar plateau. The best determinant of alveolar plateau presence in preterm infants was the expired tidal volume. Conventional sampling for pharmacokinetic clinical studies requires removal of large blood volumes from patients. This can result in a physiological/emotional burden for children. Microsampling to support pharmacokinetic clinical studies in pediatrics may reduce this burden. Parents/guardians and bedside nurses completed a questionnaire describing their perception of the use of microsampling compared to
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